Hypochlorous acid

Hypochlorous acid is an inorganic compound with the chemical formula ClOH, also written as HClO, HOCl, or ClHO. Its structure is H−O−Cl. It is an acid that forms when chlorine dissolves in water, and itself partially dissociates, forming hypochlorite anion, ClO. HClO and ClO are oxidizers, and the primary disinfection agents of chlorine solutions. HClO cannot be isolated from these solutions due to rapid equilibration with its precursor, chlorine.

Hypochlorous acid

  Hydrogen, H
  Oxygen, O
  Chlorine, Cl
Names
IUPAC name
Hypochlorous acid
Other names
  • Chloranol
  • Chloric(I) acid
  • Chlorine hydroxide
  • Chlorooxidane
  • Hydrogen hypochlorite
  • Hypochloric acid
  • Hydroxidochlorine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.029.302
EC Number
  • 232-232-5
PubChem CID
UNII
  • InChI=1S/ClHO/c1-2/h2H Y
    Key: QWPPOHNGKGFGJK-UHFFFAOYSA-N Y
  • InChI=1/ClHO/c1-2/h2H
    Key: QWPPOHNGKGFGJK-UHFFFAOYAT
SMILES
  • OCl
Properties
HOCl
Molar mass 52.46 g·mol−1
Appearance Colorless aqueous solution
Density Variable
Soluble
Acidity (pKa) 7.53
Conjugate base Hypochlorite
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
corrosive, oxidizing agent
GHS labelling:
H320, H335
P301+P330+P331, P302+P352, P304+P340, P305+P351+P338
NFPA 704 (fire diamond)
3
0
4
OX
Safety data sheet (SDS) chemfresh.com
Related compounds
Other anions
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)
Infobox references

Because of its strong antimicrobial properties, the related compounds sodium hypochlorite (NaOCl) and calcium hypochlorite (Ca(OCl)2) are ingredients in many commercial bleaches, deodorants, and disinfectants. The white blood cells of mammals, such as humans, also contain hypochlorous acid as a tool against foreign bodies. In living organisms, HOCl is generated by the reaction of hydrogen peroxide with chloride ions under the catalysis of the heme enzyme myeloperoxidase (MPO).

Like many other disinfectants, hypochlorous acid solutions will destroy pathogens, such as COVID-19, absorbed on surfaces. In low concentrations, such solutions can serve to disinfect open wounds.

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