HLA-A43

HLA-A43 (A43) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α43 subset of HLA-A α-chains. For A43, the alpha "A" chain are encoded by the HLA-A*43 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*4301. A43 and A*43 are almost synonymous in meaning. A43 is a split antigen of the broad antigen serotype A10. A43 is a sister serotype of A25, A26, A34, and A66.

Further information: History and naming of human leukocyte antigens
HLA-A43
(MHC Class I, A cell surface antigen)
HLA-A43
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*4301, β2-microglobulin
Older namesA10
Subtypes
Subtype
allele
Available structures
A43 *4301
{{{cNick2}}} *43{{{cAllele2}}}
{{{cNick3}}} *43{{{cAllele3}}}
{{{cNick4}}} *43{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

A43 is more common in Africa and SouthWest Asia. A43 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele..

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