HLA-A25

HLA-A25 (A25) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α25 subset of HLA-A α-chains. For A25, the alpha "A" chain are encoded by the HLA-A*25 allele group and the β-chain are encoded by B2M locus. This group currently is dominated by A*2501. A25 and A*25 are almost synonymous in meaning. A25 is a split antigen of the broad antigen serotype A10. A25 is a sister serotype of A26, A34, A43, and A66.

Further information: History and naming of human leukocyte antigens
HLA-A25
(MHC Class I, A cell surface antigen)
HLA-A25
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*2501, β2-microglobulin
Older namesA10
Subtypes
Subtype
allele
Available structures
A25 *2501
{{{cNick2}}} *25{{{cAllele2}}}
{{{cNick3}}} *25{{{cAllele3}}}
{{{cNick4}}} *25{{{cAllele4}}}
Alleles link-out to IMGT/HLA database at EBI

A25 is more common in SW Asia to NW Europe. A25 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele..

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