ERAP2

ERAP2
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	3SE6, 4E36, 4JBS, 5CU5, 5AB2, 5AB0
Identifiers
Aliases	ERAP2, L-RAP, LRAP, endoplasmic reticulum aminopeptidase 2
External IDs	OMIM: 609497 HomoloGene: 75183 GeneCards: ERAP2
Gene location (Human)
Chr.	Chromosome 5 (human)
End	96,919,703 bp
RNA expression pattern
	Top expressed in
	lymph node; ; superficial temporal artery; ; visceral pleura; ; monocyte; ; appendix; ; Achilles tendon; ; spleen; ; blood; ; jejunal mucosa; ; palpebral conjunctiva;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	aminopeptidase activity; metallopeptidase activity; peptidase activity; hydrolase activity; zinc ion binding; metal ion binding; peptide binding; metalloaminopeptidase activity; endopeptidase activity;
Cellular component	integral component of membrane; endoplasmic reticulum lumen; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; plasma membrane; cytoplasm;
Biological process	immune system process; adaptive immune response; proteolysis; regulation of blood pressure; antigen processing and presentation of peptide antigen via MHC class I; peptide catabolic process; antigen processing and presentation of endogenous peptide antigen via MHC class I; signal transduction; cell-cell signaling;
	Sources:Amigo / QuickGO
Orthologs
	64167
	n/a
	ENSG00000164308
	n/a
	Q6P179
	n/a
	NM_001130140; NM_022350; NM_001329229; NM_001329233
	n/a
	NP_001123612; NP_001316158; NP_001316162; NP_071745
	n/a
	Wikidata
View/Edit Human

Endoplasmic reticulum aminopeptidase 2 is an aminopeptidase in humans involved in antigen presentation. It is encoded by the ERAP2 gene.

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