EA-3148

EA-3148 (Substance 100A) is a "V-series" nerve agent related to the better-known compounds VX and VR. It was studied by both the US and Soviet chemical weapons programmes during the Cold War, and is notable as the only V-series organophosphate nerve agent specifically identified in public domain sources as having a higher absolute potency as an acetylcholinesterase inhibitor than VX (around 50% more potent by weight). However, both the US and Soviet investigations of the compound concluded that despite its high potency, the physicochemical properties of the substance made it unsuitable for weaponisation, and further research was not conducted.

EA-3148
Names
Preferred IUPAC name
O-Cyclopentyl S-[2-(diethylamino)ethyl] methylphosphonothioate
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
UNII
  • InChI=1S/C12H26NO2PS/c1-4-13(5-2)10-11-17-16(3,14)15-12-8-6-7-9-12/h12H,4-11H2,1-3H3 N
    Key: PMVOUPZOZITGTQ-UHFFFAOYSA-N N
  • InChI=1/C12H26NO2PS/c1-4-13(5-2)10-11-17-16(3,14)15-12-8-6-7-9-12/h12H,4-11H2,1-3H3
    Key: PMVOUPZOZITGTQ-UHFFFAOYAC
SMILES
  • CCN(CC)CCSP(C)(=O)OC1CCCC1
Properties
C12H26NO2PS
Molar mass 279.378 g/mol
Density 1.05 g/cm3
Boiling point 111.11 °C (232.00 °F; 384.26 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely Toxic
NFPA 704 (fire diamond)
4
1
1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references
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The chemical structure of EA-3148 falls within the scope of compounds designated "Toxic chemicals" under Schedule 1 of the Chemical Weapons Convention and so it is illegal throughout the world under international law and may only be used for certain types of scientific and medical research.

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