Dachshund (gene)

dachshund (dac) is a gene involved in the development of the arthropod compound eye which also plays a role in leg development. It is activated by the Distal-less (Dll) gene.

Dachshund
Identifiers
OrganismDrosophila melanogaster
Symboldac
UniProtQ24030
Search for
StructuresSwiss-model
DomainsInterPro

Dachshund homologue (DACH1) regulates tumorigenesis in humans as a part of the Retinal Determination Gene Network (RDGN) complex, with cancer patients showing altered DACH1 expression. Its homologs form the SKI/SNO/DAC family (Pfam PF02437).

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