Cdc25
Cdc25 is a dual-specificity phosphatase first isolated from the yeast Schizosaccharomyces pombe as a cell cycle defective mutant. As with other cell cycle proteins or genes such as Cdc2 and Cdc4, the "cdc" in its name refers to "cell division cycle". Dual-specificity phosphatases are considered a sub-class of protein tyrosine phosphatases. By removing inhibitory phosphate residues from target cyclin-dependent kinases (Cdks), Cdc25 proteins control entry into and progression through various phases of the cell cycle, including mitosis and S ("Synthesis") phase.
| M-phase inducer phosphatase | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Aliases | Cdc25 phosphatase | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 157680 GeneCards: | ||||||||||||||||||||||||||||||||||||||||||||||||||
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