5-HT₄ receptor

HTR4
Identifiers
Aliases	HTR4, 5-HT4, 5-HT4R, 5-HT4 receptor, 5-hydroxytryptamine receptor 4
External IDs	OMIM: 602164 MGI: 109246 HomoloGene: 20243 GeneCards: HTR4
Gene location (Human)
Chr.	Chromosome 5 (human)
End	148,677,235 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	62,629,648 bp
RNA expression pattern
	Top expressed in
	triceps brachii muscle; ; external globus pallidus; ; vena cava; ; vastus lateralis muscle; ; body of tongue; ; subthalamic nucleus; ; spongy bone; ; orbitofrontal cortex; ; thymus; ; parotid gland;
	Top expressed in
	mucosa of urinary bladder; ; olfactory tubercle; ; left colon; ; Paneth cell; ; Region I of hippocampus proper; ; intestinal villus; ; entorhinal cortex; ; dentate gyrus; ; nucleus accumbens; ; hippocampus proper;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; G protein-coupled serotonin receptor activity; trace-amine receptor activity; identical protein binding; neurotransmitter receptor activity; protein binding;
Cellular component	cytoplasm; integral component of membrane; endosome; plasma membrane; integral component of plasma membrane; membrane; dendrite;
Biological process	gamma-aminobutyric acid signaling pathway; G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; regulation of appetite; signal transduction; chemical synaptic transmission; G protein-coupled serotonin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3360
	15562
	ENSG00000164270
	ENSMUSG00000026322
	Q13639
	P97288
NM_000870; NM_001040169; NM_001040172; NM_001040173; NM_001040174;
	NM_001286410; NM_199453
	NM_008313; NM_001364956; NM_001364957; NM_001364958; NM_001364959
NP_000861; NP_001035259; NP_001035262; NP_001035263; NP_001273339;
	NP_955525
	NP_032339; NP_001351885; NP_001351886; NP_001351887; NP_001351888
	Wikidata
View/Edit Human	View/Edit Mouse

5-Hydroxytryptamine receptor 4 is a protein that in humans is encoded by the HTR4 gene.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

5-HT4 receptor

5-HT₄ receptor