Glucuronosyltransferase
Uridine 5'-diphospho-glucuronosyltransferase (UDP-glucuronosyltransferase, UGT) is a microsomal glycosyltransferase (EC 2.4.1.17) that catalyzes the transfer of the glucuronic acid component of UDP-glucuronic acid to a small hydrophobic molecule. This is a glucuronidation reaction.
| Glucuronosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Glucuronosyltransferase monomer, Xanthomonas campestris | |||||||||
| Identifiers | |||||||||
| EC no. | 2.4.1.17 | ||||||||
| CAS no. | 9030-08-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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| UDP-glucuronosyl and UDP-glucosyl transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. | |||||||||
| Identifiers | |||||||||
| Symbol | UDPGT | ||||||||
| Pfam | PF00201 | ||||||||
| InterPro | IPR002213 | ||||||||
| PROSITE | PDOC00359 | ||||||||
| SCOP2 | 1rrv / SCOPe / SUPFAM | ||||||||
| Membranome | 476 | ||||||||
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Alternative names:
- glucuronyltransferase
- UDP-glucuronyl transferase
- UDP-GT
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