Excitatory amino acid transporter 3

SLC1A1
Identifiers
Aliases	SLC1A1, EAAC1, EAAT3, SCZD18, DCBXA, solute carrier family 1 member 1
External IDs	OMIM: 133550 MGI: 105083 HomoloGene: 20881 GeneCards: SLC1A1
Gene location (Human)
Chr.	Chromosome 9 (human)
End	4,587,469 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	28,891,360 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; jejunal mucosa; ; kidney tubule; ; pancreatic ductal cell; ; duodenum; ; lower lobe of lung; ; postcentral gyrus; ; endothelial cell; ; superior frontal gyrus; ; caput epididymis;
	Top expressed in
	retinal pigment epithelium; ; subiculum; ; lateral geniculate nucleus; ; kidney; ; medial geniculate nucleus; ; Region I of hippocampus proper; ; proximal tubule; ; medial dorsal nucleus; ; anterior horn of spinal cord; ; hippocampus proper;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	cysteine transmembrane transporter activity; protein binding; symporter activity; L-glutamate transmembrane transporter activity; glutamate binding; amino acid transmembrane transporter activity; high-affinity glutamate transmembrane transporter activity; chloride transmembrane transporter activity; glutamate:sodium symporter activity; metal ion binding;
Cellular component	integral component of membrane; membrane; plasma membrane; apical plasma membrane; extracellular exosome; integral component of plasma membrane; early endosome membrane; recycling endosome membrane;
Biological process	chemical synaptic transmission; D-aspartate import across plasma membrane; ion transport; positive regulation of heart rate; glutamate secretion; cysteine transport; protein homooligomerization; L-glutamate import; L-glutamate transmembrane transport; cysteine transmembrane transport; L-aspartate import across plasma membrane; chloride transmembrane transport; L-glutamate import across plasma membrane; amino acid transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	6505
	20510
	ENSG00000106688
	ENSMUSG00000024935
	P43005
	P51906
	NM_004170
	NM_009199
	NP_004161
	NP_033225
	Wikidata
View/Edit Human	View/Edit Mouse

Excitatory amino acid transporter 3 (EAAT3), is a protein that in humans is encoded by the SLC1A1 gene.

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