Human T-lymphotropic virus 2

A virus closely related to HTLV-I, human T-lymphotropic virus 2 (HTLV-II) shares approximately 70% genomic homology (structural similarity) with HTLV-I. It was discovered by Robert Gallo and colleagues.

Human T-lymphotropic virus 2
SpecialtyInfectious diseases
SymptomsMild cognitive Impairment, Mycosis fungoides
DurationChronic, incurable
CausesHTLV-2
Risk factorsUnsafe sex, haemophiliacs
Diagnostic methodBlood test
Differential diagnosisHIV/AIDS, Lymphoma, HTLV-1
PreventionPracticing safe-sex, use of clean needles, screening blood transfusions, Avoiding breastfeeding.
MedicationAntiretrovirals, chemotherapy
Prognosis95% present with no symptoms, generally good
Frequency15-20 million people worldwide
Primate T-lymphotropic virus 2
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Genus: Deltaretrovirus
Species:
Primate T-lymphotropic virus 2

HTLV-2 is prevalent among the indigenous populations in Africa and the Indian-American tribes in Central and South America as well as among drug users in Europe and North America It can be passed down from mother to child through breastmilk and genetically as well from either parent.

HTLV-II entry in target cells is mediated by the glucose transporter GLUT1.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.