Human T-lymphotropic virus 2
A virus closely related to HTLV-I, human T-lymphotropic virus 2 (HTLV-II) shares approximately 70% genomic homology (structural similarity) with HTLV-I. It was discovered by Robert Gallo and colleagues.
Human T-lymphotropic virus 2 | |
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Specialty | Infectious diseases |
Symptoms | Mild cognitive Impairment, Mycosis fungoides |
Duration | Chronic, incurable |
Causes | HTLV-2 |
Risk factors | Unsafe sex, haemophiliacs |
Diagnostic method | Blood test |
Differential diagnosis | HIV/AIDS, Lymphoma, HTLV-1 |
Prevention | Practicing safe-sex, use of clean needles, screening blood transfusions, Avoiding breastfeeding. |
Medication | Antiretrovirals, chemotherapy |
Prognosis | 95% present with no symptoms, generally good |
Frequency | 15-20 million people worldwide |
Primate T-lymphotropic virus 2 | |
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Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Pararnavirae |
Phylum: | Artverviricota |
Class: | Revtraviricetes |
Order: | Ortervirales |
Family: | Retroviridae |
Genus: | Deltaretrovirus |
Species: | Primate T-lymphotropic virus 2 |
HTLV-2 is prevalent among the indigenous populations in Africa and the Indian-American tribes in Central and South America as well as among drug users in Europe and North America It can be passed down from mother to child through breastmilk and genetically as well from either parent.
HTLV-II entry in target cells is mediated by the glucose transporter GLUT1.
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