Lafayette–Opelousas–Morgan City combined statistical area

The Lafayette–Opelousas–Morgan City combined statistical area is made up of seven parishes in the Acadiana region of southern Louisiana. The statistical area consists of the Lafayette Metropolitan Statistical Area (MSA) and two micropolitical statistical areas (μSAs) – Opelousas, Louisiana Micropolitical Statistical Area and Morgan City, Louisiana Micropolitical Statistical Area. The region consists of seven parishes: Acadia, Iberia, Lafayette, St. Landry, St. Martin, St. Mary, and Vermilion Parishes. As of the 2010 census, the CSA had a population of 604,784 (though a 2015 estimate placed the population at 627,146).

The CSA is home to a large Cajun population and is also known as the "Cajun heartland".