Lady Byrne

Anne-Marie, Lady Byrne is a fictional character from the BBC medical drama Holby City, portrayed by actress Jane Asher. The character first appeared on 10 May 2007 in episode "After the Fall" - series 9, episode 30 of the programme. After several guest appearances as the mother of established character Joseph Byrne throughout series 9 and 10, Asher signed a three-month contract to become a series regular from May 2008 onwards, for a period of 10 episodes. Her initial storyline saw her son's girlfriend, Jac Naylor, embark on an affair with Anne-Marie's husband and Joseph's father, Lord Byrne - eventually culminating in his death, and leaving the character a widow. Upon her return to the programme, she takes over Lord Byrne's position as Executive Chairman of the Byrne Foundation – a charity committed to research into Cardiac Valve Disease.