Ketoprofen

Ketoprofen is one of the propionic acid class of nonsteroidal anti-inflammatory drugs (NSAID) with analgesic and antipyretic effects. It acts by inhibiting the body's production of prostaglandin.

Ketoprofen
Clinical data
Trade namesOruvail, others
AHFS/Drugs.comMonograph
MedlinePlusa686014
License data
Pregnancy
category
  • AU: C
Routes of
administration
By mouth, topical, intravenous
ATC code
Legal status
Legal status
  • AU: S3 (Pharmacist only) / S4
  • CA: ℞-only
  • US: WARNINGRx-only
  • Rx-only & OTC
Pharmacokinetic data
Protein binding99%
Elimination half-life2–2.5 hours
Identifiers
  • (RS)-2-(3-benzoylphenyl)propanoic acid
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.040.676
Chemical and physical data
FormulaC16H14O3
Molar mass254.285 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
SMILES
  • CC(c1cccc(c1)C(=O)c2ccccc2)C(=O)O
  • InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19) Y
  • Key:DKYWVDODHFEZIM-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

It was patented in 1967 and approved for medical use in 1980.

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