KPNB1

KPNB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1F59, 1IBR, 1M5N, 1O6O, 1O6P, 1QGK, 1QGR, 2P8Q, 2Q5D, 2QNA, 3LWW, 3W5K
Identifiers
Aliases	KPNB1, IMB1, IPO1, IPOB, Impnb, NTF97, karyopherin subunit beta 1
External IDs	OMIM: 602738 MGI: 107532 HomoloGene: 1707 GeneCards: KPNB1
Gene location (Human)
Chr.	Chromosome 17 (human)
End	47,685,505 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	97,078,707 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; optic nerve; ; secondary oocyte; ; islet of Langerhans; ; stromal cell of endometrium; ; internal globus pallidus; ; appendix; ; middle temporal gyrus; ; Brodmann area 23; ; superficial temporal artery;
	Top expressed in
	condyle; ; fossa; ; primitive streak; ; medullary collecting duct; ; abdominal wall; ; ureter; ; yolk sac; ; renal corpuscle; ; vas deferens; ; cumulus cell;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	Hsp90 protein binding; protein domain specific binding; zinc ion binding; protein binding; nuclear localization sequence binding; enzyme binding; RNA binding; importin-alpha family protein binding;
Cellular component	nuclear membrane; membrane; nuclear periphery; nuclear pore; endoplasmic reticulum tubular network; nucleoplasm; extracellular exosome; nucleus; nuclear envelope; extracellular region; cytoplasm; cytosol; specific granule lumen; ficolin-1-rich granule lumen; host cell; cytoplasmic stress granule; protein-containing complex;
Biological process	intracellular transport of virus; apoptotic DNA fragmentation; Ran protein signal transduction; establishment of protein localization; mitotic spindle assembly; protein transport; mitotic metaphase plate congression; intracellular protein transport; astral microtubule organization; mitotic chromosome movement towards spindle pole; establishment of mitotic spindle localization; NLS-bearing protein import into nucleus; modulation by virus of host cellular process; protein import into nucleus; ribosomal protein import into nucleus; viral process; neutrophil degranulation; regulation of cholesterol biosynthetic process; transport;
	Sources:Amigo / QuickGO
Orthologs
	3837
	16211
	ENSG00000108424
	ENSMUSG00000001440
	Q14974
	P70168
	NM_002265; NM_001276453
	NM_008379
	NP_001263382; NP_002256
	NP_032405
	Wikidata
View/Edit Human	View/Edit Mouse

Importin subunit beta-1 is a protein that in humans is encoded by the KPNB1 gene.

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