FERMT1

FERMT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KMC, 4BBK
Identifiers
Aliases	FERMT1, C20orf42, DTGCU2, KIND1, UNC112A, URP1, fermitin family member 1, FERM domain containing kindlin 1
External IDs	OMIM: 607900 MGI: 2443583 HomoloGene: 9773 GeneCards: FERMT1
Gene location (Human)
Chr.	Chromosome 20 (human)
End	6,123,030 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	132,787,826 bp
RNA expression pattern
	Top expressed in
	hair follicle; ; rectum; ; pancreatic ductal cell; ; nipple; ; human penis; ; secondary oocyte; ; left adrenal gland; ; oral cavity; ; vulva; ; jejunal mucosa;
	Top expressed in
	colon; ; stomach; ; proximal tubule; ; jejunum; ; ileum; ; duodenum; ; kidney; ; urethra; ; zone of skin; ; lip;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	actin filament binding;
Cellular component	cell projection; ruffle membrane; cytosol; cell junction; filamentous actin; plasma membrane; membrane; focal adhesion; cytoplasm; cytoskeleton;
Biological process	keratinocyte proliferation; cell adhesion; keratinocyte migration; establishment of epithelial cell polarity; positive regulation of cell-matrix adhesion; negative regulation of gene expression; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell adhesion mediated by integrin; negative regulation of protein import into nucleus; negative regulation of timing of anagen; basement membrane organization; negative regulation of canonical Wnt signaling pathway; negative regulation of stem cell proliferation; integrin-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	55612
	241639
	ENSG00000101311
	ENSMUSG00000027356
	Q9BQL6
	P59113
	NM_017671
	NM_198029
	NP_060141
	NP_932146
	Wikidata
View/Edit Human	View/Edit Mouse

Fermitin family homolog 1 is a protein that in humans is encoded by the FERMT1 gene.

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