Joseph L. Goldstein

Joseph Leonard Goldstein ForMemRS (born April 18, 1940) is an American biochemist. He received the Nobel Prize in Physiology or Medicine in 1985, along with fellow University of Texas Southwestern researcher, Michael Brown, for their studies regarding cholesterol. They discovered that human cells have low-density lipoprotein (LDL) receptors that remove cholesterol from the blood and that when LDL receptors are not present in sufficient numbers, individuals develop hypercholesterolemia and become at risk for cholesterol related diseases, notably coronary heart disease. Their studies led to the development of statin drugs.

For other people named Joseph Goldstein, see Joseph Goldstein (disambiguation).
Joseph L. Goldstein
Born
Joseph Leonard Goldstein

(1940-04-18) April 18, 1940
Kingstree, South Carolina
Alma mater
  • Washington and Lee University
  • University of Texas Southwestern Medical Center
Known forcholesterol
Awards
  • Heinrich Wieland Prize (1974)
  • Richard Lounsbery Award (1979)
  • Louisa Gross Horwitz Prize (1984)
  • Nobel Prize in Physiology or Medicine (1985)
  • William Allan Award (1985)
  • National Medal of Science (1988)
  • ForMemRS (1991)
Scientific career
Fieldsbiochemistry
InstitutionsUniversity of Texas Southwestern Medical Center
Websiteprofiles.utsouthwestern.edu/profile/12645/joseph-goldstein.html
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