James P. Allison
James Patrick Allison (born August 7, 1948) is an American immunologist and Nobel laureate who holds the position of professor and chair of immunology and executive director of immunotherapy platform at the MD Anderson Cancer Center at the University of Texas.
James Allison | |
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Allison at the Nobel press conference in Stockholm, December 2018 | |
Born | James Patrick Allison August 7, 1948 Alice, Texas, U.S. |
Education | University of Texas, Austin (BS, MS, PhD) |
Known for | Cancer immunotherapy |
Spouses | Malinda Bell
(m. 1969; div. 2012)Padmanee Sharma (m. 2014) |
Children | 1 |
Awards | Breakthrough Prize in Life Sciences (2014) Massry Prize (2014) Tang Prize (2014) Louisa Gross Horwitz Prize (2014) Harvey Prize (2014) Gairdner Foundation International Award (2014) Paul Ehrlich and Ludwig Darmstaedter Prize (2015) Lasker-DeBakey Clinical Medical Research Award (2015) Wolf Prize (2017) Warren Alpert Foundation Prize(2017) Balzan Prize (2017) Sjöberg Prize (2017) King Faisal International Prize (2018) Albany Medical Center Prize (2018) Dr. Paul Janssen Award for Biomedical Research (2018) Nobel Prize in Physiology or Medicine (2018) |
Scientific career | |
Fields | Immunology |
Institutions | M. D. Anderson Cancer Center Weill Cornell Medicine University of California, Berkeley University of California, San Francisco University of Texas at Austin |
Thesis | Studies on bacterial asparaginases: I. Isolation and characterization of a tumor inhibitory asparaginase from Alcaligenes ?Eutrophus. II. Insolubilization of L-Asparaginase by covalent attachment to nylon tubing (1973) |
Doctoral advisor | Barrie Kitto |
His discoveries have led to new cancer treatments for the deadliest cancers. He is also the director of the Cancer Research Institute (CRI) scientific advisory council. He has a longstanding interest in mechanisms of T-cell development and activation, the development of novel strategies for tumor immunotherapy, and is recognized as one of the first people to isolate the T-cell antigen receptor complex protein.
In 2014, he was awarded the Breakthrough Prize in Life Sciences; in 2018, he shared the Nobel Prize in Physiology or Medicine with Tasuku Honjo.