Intravenous sodium bicarbonate

Intravenous sodium bicarbonate
Clinical data
Trade names	many
Other names	sodium hydrogen carbonate, monosodium carbonate
AHFS/Drugs.com	Monograph
MedlinePlus	a682001
License data	US DailyMed: Sodium_bicarbonate;
Routes of; administration	intravenous
ATC code	B05XA02 (WHO) B05CB04 (WHO);
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Bioavailability	100% (intravenous)
Identifiers
	IUPAC name sodium hydrogen carbonate;
CAS Number	144-55-8 ;
PubChem CID	516892;
DrugBank	DB01390 ;
ChemSpider	8609 ;
UNII	8MDF5V39QO;
KEGG	D01203; C12603;
ChEBI	CHEBI:32139;
ChEMBL	ChEMBL1353;
Chemical and physical data
Formula	CHNaO3
Molar mass	84.006 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C(=O)(O)[O-].[Na+];
	InChI InChI=1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1; Key:UIIMBOGNXHQVGW-UHFFFAOYSA-M;
	(what is this?) (verify)

Intravenous sodium bicarbonate, also known as sodium hydrogen carbonate, is a medication primarily used to treat severe metabolic acidosis. For this purpose it is generally only used when the pH is less than 7.1 and when the underlying cause is either diarrhea, vomiting, or the kidneys. Other uses include high blood potassium, tricyclic antidepressant overdose, and cocaine toxicity as well as a number of other poisonings. It is given by injection into a vein.

Side effects may include low blood potassium, high blood sodium, and swelling. It is not recommended in people with low blood calcium. Sodium bicarbonate is in the alkalinizing family of medication. It works by increasing blood bicarbonate, which buffers excess hydrogen ion and raises blood pH.

Commercial production of sodium bicarbonate began between 1791 and 1823. Intravenous medical use began around the 1950s. It is on the World Health Organization's List of Essential Medicines. Sodium bicarbonate is available as a generic medication.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.