Interstate 395 (Connecticut–Massachusetts)

Interstate 395 (I-395) is an auxiliary Interstate Highway in the U.S. states of Connecticut and Massachusetts; it is maintained by the Connecticut Department of Transportation (CTDOT) and the Massachusetts Department of Transportation (MassDOT). Spanning nearly 67 miles (108 km) on a south–north axis, it is the only spur route of I-95 in Connecticut. The 36-mile (58 km) section between its splits from I-95 in East Lyme and Connecticut Route 695 in Plainfield is a component highway of the Connecticut Turnpike. Within that state, the highway is named the American Ex-Prisoner of War Memorial Highway from Plainfield to Thompson.

The highway was first established as part of the Connecticut Turnpike in 1958, while the Connecticut Route 52 designation was applied to the portion north of the turnpike in 1967. Connecticut Route 52 was intended to become a southern extension of I-290, although the current designation of I-395 was ultimately assigned in 1983.