IL17RD

IL17RD
Identifiers
Aliases	IL17RD, HH18, IL-17RD, IL17RLM, SEF, interleukin 17 receptor D
External IDs	OMIM: 606807 MGI: 2159727 HomoloGene: 9717 GeneCards: IL17RD
Gene location (Human)
Chr.	Chromosome 3 (human)
End	57,170,306 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	26,829,243 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; lactiferous duct; ; ganglionic eminence; ; corpus epididymis; ; parietal pleura; ; germinal epithelium; ; sperm; ; endothelial cell; ; saphenous vein; ; myometrium;
	Top expressed in
	primitive streak; ; Bowman's capsule; ; secondary oocyte; ; maxillary prominence; ; ciliary body; ; trigeminal ganglion; ; aortic valve; ; abdominal wall; ; retinal pigment epithelium; ; iris;
	More reference expression data
	n/a
Gene ontology
Molecular function	interleukin-17 receptor activity;
Cellular component	cytoplasm; integral component of membrane; Golgi apparatus; membrane; Golgi membrane; plasma membrane; integral component of plasma membrane; nucleoplasm;
Biological process	MAPK cascade; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	54756
	171463
	ENSG00000144730
	ENSMUSG00000040717
	Q8NFM7
	Q8JZL1
	NM_017563; NM_001318864
	NM_027265; NM_134437
	NP_001305793; NP_060033
	NP_602319
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin 17 receptor D (also known as Sef) is a protein that in humans is encoded by the IL17RD gene.

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. Alternate splicing generates multiple transcript variants encoding distinct isoforms. IL-17RD has been described to limit fibroblast growth factor receptor (FGFR) signaling and to be a part of the IL-17 receptor signaling complex.

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