Interleukin-5 receptor
The interleukin-5 receptor is a type I cytokine receptor. It is a heterodimer of the interleukin 5 receptor alpha subunit and CSF2RB.
| interleukin 5 receptor, alpha | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL5RA | ||||||
| Alt. symbols | IL5R | ||||||
| NCBI gene | 3568 | ||||||
| HGNC | 6017 | ||||||
| OMIM | 147851 | ||||||
| RefSeq | NM_175725 | ||||||
| UniProt | Q01344 | ||||||
| Other data | |||||||
| Locus | Chr. 3 p26-p24 | ||||||
| |||||||
| colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CSF2RB | ||||||
| Alt. symbols | IL3RB | ||||||
| NCBI gene | 1439 | ||||||
| HGNC | 2436 | ||||||
| OMIM | 138981 | ||||||
| RefSeq | NM_000395 | ||||||
| UniProt | P32927 | ||||||
| Other data | |||||||
| Locus | Chr. 22 q12.2-13.1 | ||||||
| |||||||
The IL-5 receptor (IL-5R) belongs to the type I cytokine receptor family and is a heterodimer composed of two polypeptide chains, one α subunit, which binds IL-5 and confers upon the receptor cytokine specificity, and one β subunit, which contains the signal transduction domains.
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