IL1F10

IL1F10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5BOW
Identifiers
Aliases	IL1F10, FIL1-theta, IL-1HY2, IL-38, IL1-theta, IL1HY2, FKSG75, interleukin 1 family member 10 (theta), interleukin 1 family member 10
External IDs	OMIM: 615296 MGI: 2652548 HomoloGene: 17690 GeneCards: IL1F10
Gene location (Human)
Chr.	Chromosome 2 (human)
End	113,075,843 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	24,183,832 bp
RNA expression pattern
	Top expressed in
	skin of limb; ; skin of abdomen; ; human penis; ; amniotic fluid; ; pharynx; ; thymus; ; placenta; ; head; ; exocrine gland; ; mouth;
	Top expressed in
	lip; ; skin of abdomen; ; skin of back; ; hair follicle; ; cervix; ; thymus;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine activity; interleukin-1 receptor binding;
Cellular component	extracellular space; extracellular region;
Biological process	inflammatory response; immune response; regulation of signaling receptor activity; cytokine-mediated signaling pathway; cellular response to cytokine stimulus; neutrophil chemotaxis; positive regulation of interleukin-6 production; positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of JNK cascade; cellular response to lipopolysaccharide;
	Sources:Amigo / QuickGO
Orthologs
	84639
	215274
	ENSG00000136697
	ENSMUSG00000046845
	Q8WWZ1
	Q8R459
	NM_173161; NM_032556
	NM_153077
	NP_115945; NP_775184
	NP_694717
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-1 family member 10 is a protein that in humans is encoded by the IL1F10 gene.

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported.

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