Holy See–United States relations

The current United States Ambassador to the Holy See is Joe Donnelly, who replaced the ad interim Chargé d'Affaires, Patrick Connell, on April 11, 2021. The Holy See is represented by its apostolic nuncio, Cardinal Christophe Pierre, who assumed office on April 12, 2016. The U.S. Embassy to the Holy See is located in Rome, in the Villa Domiziana. The Nunciature to the United States is located in Washington, D.C., at 3339 Massachusetts Avenue, N.W.