Haematin

Haematin (also known as hematin, ferriheme, hematosin, hydroxyhemin, oxyheme, phenodin, or oxyhemochromogen) is a dark bluish or brownish pigment containing iron in the ferric state, obtained by the oxidation of haem.

Not to be confused with haematein.

Haematin inhibits the synthesis of porphyrin (by repressing ALAS1 synthesis), and stimulates the synthesis of globin. For this reason, it is used in the treatment of porphyrias.

It is a component of cytochromes and peroxidases. Haematin derived synthetically from hemin is used as a reagent.

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