Haemophilia C
Haemophilia C (also known as plasma thromboplastin antecedent (PTA) deficiency or Rosenthal syndrome) is a mild form of haemophilia affecting both sexes, due to factor XI deficiency. It predominantly occurs in Ashkenazi Jews. It is the fourth most common coagulation disorder after von Willebrand's disease and haemophilia A and B. In the United States, it is thought to affect 1 in 100,000 of the adult population, making it 10% as common as haemophilia A.
| Haemophilia C | |
|---|---|
| Other names | Plasma thromboplastin antecedent (PTA) deficiency, Rosenthal syndrome |
| Haemophilia C caused by deficiency in Factor XI | |
| Specialty | Haematology |
| Symptoms | Oral bleeding |
| Causes | Deficiency of coagulation factor XI |
| Diagnostic method | Prothrombin time |
| Prevention | Physical activity precautions |
| Treatment | tranexamic acid |
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