HU-210

HU-210
Clinical data
Other names	1,1-Dimethylheptyl- 11-hydroxy- tetrahydrocannabinol
Legal status
Legal status	CA: Schedule II; UK: Class B; US: Schedule I;
Identifiers
	IUPAC name (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6H,6aH,7H,10H,10aH-benzo[c]isochromen-1-ol;
CAS Number	112830-95-2 ;
PubChem CID	9821569;
IUPHAR/BPS	731;
ChemSpider	7997318 ;
UNII	191042422P;
ChEMBL	ChEMBL307696 ;
CompTox Dashboard (EPA)	DTXSID30150188 ;
Chemical and physical data
Formula	C25H38O3
Molar mass	386.576 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCCCCCC(C)(C)C1=CC2=C([C@@H]3CC(=CC[C@H]3C(O2)(C)C)CO)C(=C1)O;
	InChI InChI=1S/C25H38O3/c1-6-7-8-9-12-24(2,3)18-14-21(27)23-19-13-17(16-26)10-11-20(19)25(4,5)28-22(23)15-18/h10,14-15,19-20,26-27H,6-9,11-13,16H2,1-5H3/t19-,20-/m1/s1 ; Key:SSQJFGMEZBFMNV-WOJBJXKFSA-N ;
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HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 has a binding affinity of 0.061 nM at CB₁ and 0.52 nM at CB₂ in cloned human cannabinoid receptors compared to delta-9-THC of 40.7 nM at CB₁. HU-210 is the (–)-1,1-dimethylheptyl analog of 11-hydroxy- Δ⁸- tetrahydrocannabinol; in some references it is called 1,1-dimethylheptyl- 11-hydroxytetrahydrocannabinol. The abbreviation "HU" stands for Hebrew University.

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