HNRPD

HNRNPD
Available structures
PDB	Ortholog search: D6RF44 PDBe D6RF44 RCSB
List of PDB id codes
	1HD0, 1HD1, 1IQT, 1WTB, 1X0F, 2Z5N
Identifiers
Aliases	HNRNPD, AUF1, AUF1A, HNRPD, P37, hnRNPD0, heterogeneous nuclear ribonucleoprotein D
External IDs	OMIM: 601324 MGI: 101947 HomoloGene: 22410 GeneCards: HNRNPD
Gene location (Human)
Chr.	Chromosome 4 (human)
End	82,374,503 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	100,126,797 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; pylorus; ; endometrium; ; lactiferous duct; ; germinal epithelium; ; thymus; ; visceral pleura; ; parietal pleura; ; lymph node; ; thymus;
	Top expressed in
	maxillary prominence; ; abdominal wall; ; ganglionic eminence; ; somite; ; atrium; ; primitive streak; ; thymus; ; medial ganglionic eminence; ; yolk sac; ; hair follicle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	telomeric DNA binding; protein binding; minor groove of adenine-thymine-rich DNA binding; mRNA binding; histone deacetylase binding; transcription factor binding; chromatin binding; mRNA 3'-UTR AU-rich region binding; DNA binding; nucleic acid binding; RNA binding; sequence-specific DNA binding; sequence-specific double-stranded DNA binding;
Cellular component	cytoplasm; cytosol; extracellular exosome; nucleoplasm; nucleus; synapse; ribonucleoprotein complex;
Biological process	response to electrical stimulus; hepatocyte dedifferentiation; cellular response to amino acid stimulus; positive regulation of transcription, DNA-templated; response to estradiol; mRNA stabilization; response to rapamycin; cellular response to putrescine; cerebellum development; negative regulation of gene expression; mRNA splicing, via spliceosome; positive regulation of translation; RNA processing; liver development; transcription, DNA-templated; regulation of circadian rhythm; response to calcium ion; response to sodium phosphate; 3'-UTR-mediated mRNA destabilization; regulation of mRNA stability; cellular response to nitric oxide; rhythmic process; cellular response to estradiol stimulus; brain development; RNA catabolic process; circadian regulation of translation; regulation of transcription, DNA-templated; positive regulation of gene expression; mRNA transcription by RNA polymerase II; positive regulation of telomere capping; positive regulation of telomerase RNA reverse transcriptase activity; regulation of telomere maintenance; RNA metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	3184
	11991
	ENSG00000138668
	ENSMUSG00000000568
	Q14103
	Q60668
	NM_031370; NM_001003810; NM_002138; NM_031369
	NM_001077265; NM_001077266; NM_001077267; NM_007516
	NP_001003810; NP_002129; NP_112737; NP_112738
	NP_001070733; NP_001070734; NP_001070735; NP_031542
	Wikidata
View/Edit Human	View/Edit Mouse

Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD) also known as AU-rich element RNA-binding protein 1 (AUF1) is a protein that in humans is encoded by the HNRNPD gene. Alternative splicing of this gene results in four transcript variants.

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