HLA-DQ7
HLA-DQ7 (DQ7) is an HLA-DQ serotype that recognizes the common HLA DQB1*0301 and the less common HLA DQB1*0304 gene products. DQ7 is a form of 'split antigen' of the broad antigen group DQ3 which also contains DQ8 and DQ9.
major histocompatibility complex, class II, DQ7 | |
| Haplotypes | DQA1*03:02:DQB1*03:01 DQA1*03:03:DQB1*03:01 DQA1*04:01:DQB1*03:01 DQA1*05:05:DQB1*03:01 DQA1*06:01:DQB1*03:01 |
| Structure (See HLA-DQ) | |
| Identifiers | alpha 1 *0302 *0303 *0401 *0505 *0601 |
| Symbol(s) | HLA-DQA1 |
| EBI-HLA | DQA1*0302 |
| EBI-HLA | DQA1*0303 |
| EBI-HLA | DQA1*0401 |
| EBI-HLA | DQA1*0505 |
| EBI-HLA | DQA1*0601 |
| Identifiers | beta 1 *0301 *0304 |
| Symbol(s) | HLA-DQB1 |
| EBI-HLA | DQB1*0301 |
| EBI-HLA | DQB1*0304 |
| Shared data | |
| Locus | chr.6 6p21.31 |
DQ7 is linked by haplotype to a number of DQA1 (DQ alpha chain) genes, producing in cis-haplotype form, a large number of DQ αβ isoforms. These DQ alpha chains are also known to form transhaplotype isomers with other HLA-DQ.
DQ7 is linked to the following alpha chains genes (DQA1*)
- 03 – *0301, *0302, *0303
- 0401
- 0505
- 0601
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