HLA-B27
Human leukocyte antigen (HLA) B27 (subtypes B*2701-2759) is a class I surface molecule encoded by the B locus in the major histocompatibility complex (MHC) on chromosome 6 and presents antigenic peptides (derived from self and non-self antigens) to T cells. HLA-B27 is strongly associated with ankylosing spondylitis and other associated inflammatory diseases, such as psoriatic arthritis, inflammatory bowel disease, and reactive arthritis.
| B*2705-β2MG with bound peptide 2bst | ||
major histocompatibility complex (human), class I, B27 | ||
| Alleles | B*2701, 2702, 2703, . . . | |
| Structure (See HLA-B) | Available 3D structures | |
| EBI-HLA | B*2701 Archived 2009-02-20 at the Wayback Machine | |
| B*2702 Archived 2009-02-20 at the Wayback Machine | ||
| B*2703 Archived 2009-02-20 at the Wayback Machine | ||
| B*2704 Archived 2009-02-20 at the Wayback Machine | ||
| B*2705 Archived 2009-02-20 at the Wayback Machine | 2bsr, 2bss, 2bst, 2a83, 1w0v, 1uxs, 1ogt, 1hsa, 1jgd, 1jge | |
| B*2706 Archived 2009-02-20 at the Wayback Machine | ||
| B*2709 Archived 2009-02-20 at the Wayback Machine | 1w0w, 1uxw, 1of2, 1k5n | |
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