HLA-A74

HLA-A74 (A74) is a human leukocyte antigen serotype within HLA-A serotype group. The serotype is determined by the antibody recognition of α74 subset of HLA-A α-chains. For A74, the alpha "A" chain are encoded by the HLA-A*74 allele group and the β-chain are encoded by B2M locus. A74 and A*74 are almost synonymous in meaning. A74 is a split antigen of the broad antigen serotype A19. A74 is a sister serotype of A29, A30, A31, A32, and A33.

Further information: History and naming of human leukocyte antigens
HLA-A74
(MHC Class I, A cell surface antigen)
HLA-A74
About
Proteintransmembrane receptor/ligand
Structureαβ heterodimer
SubunitsHLA-A*74--, β2-microglobulin
Subtypes
Subtype
allele
Available structures
A74 *7401
{{{cNick2}}} *74{{{cAllele2}}}
{{{cNick3}}} *74{{{cAllele3}}}
{{{cNick4}}} *74{{{cAllele4}}}
Rare alleles
Subtype
allele
Available structures
A74.3 *7403
{{{rnick2}}} *74{{{rallele2}}}
{{{rnick3}}} *74{{{rallele3}}}
Alleles link-out to IMGT/HLA database at EBI

A74 is more common in Subsaharan Africa. A74 is a rare HLA-A allele group.

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