HBXIP

LAMTOR5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3MS6, 3MSH
Identifiers
Aliases	LAMTOR5, HBXIP, XIP, late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
External IDs	OMIM: 608521 MGI: 1915826 HomoloGene: 4668 GeneCards: LAMTOR5
Gene location (Human)
Chr.	Chromosome 1 (human)
End	110,407,942 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	107,191,398 bp
RNA expression pattern
	Top expressed in
	kidney tubule; ; kidney; ; islet of Langerhans; ; palpebral conjunctiva; ; monocyte; ; left ventricle; ; anterior pituitary; ; glomerulus; ; renal medulla; ; metanephric glomerulus;
	Top expressed in
	yolk sac; ; facial motor nucleus; ; medial ganglionic eminence; ; proximal tubule; ; kidney; ; endocardial cushion; ; anterior horn of spinal cord; ; extraocular muscle; ; adrenal gland; ; otic placode;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity; protein binding; molecular adaptor activity;
Cellular component	cytoplasm; cytosol; Ragulator complex; lysosomal membrane; lysosome;
Biological process	regulation of cell size; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; viral genome replication; response to virus; negative regulation of apoptotic process; protein localization to lysosome; cellular response to amino acid stimulus; positive regulation of TOR signaling; regulation of macroautophagy; positive regulation of TORC1 signaling;
	Sources:Amigo / QuickGO
Orthologs
	10542
	68576
	ENSG00000134248
	ENSMUSG00000087260
	O43504
	Q9D1L9
	NM_006402; NM_001382293
	NM_026774
	NP_006393; NP_001369222; NP_006393.2
	NP_081050
	Wikidata
View/Edit Human	View/Edit Mouse

Hepatitis B virus X-interacting protein is a protein that in humans is encoded by the HBXIP gene.

This gene encodes a protein that specifically complexes with the C-terminus of hepatitis B virus X protein (HBx). The function of this protein is to negatively regulate HBx activity and thus to alter the replication life cycle of the virus.

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