Growth hormone–releasing hormone
Growth hormone–releasing hormone (GHRH), also known as somatocrinin or by several other names in its endogenous forms and as somatorelin (INN) in its pharmaceutical form, is a releasing hormone of growth hormone (GH). It is a 44-amino acid peptide hormone produced in the arcuate nucleus of the hypothalamus.
| Growth hormone releasing hormone | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | GHRH | ||||||
| Alt. symbols | GRF, GHRF | ||||||
| CAS number | |||||||
| NCBI gene | 2691 | ||||||
| HGNC | 4265 | ||||||
| OMIM | 139190 | ||||||
| RefSeq | NM_021081 | ||||||
| UniProt | P01286 | ||||||
| Other data | |||||||
| Locus | Chr. 20 p12 or q11.2-q12 | ||||||
| |||||||
GHRH first appears in the human hypothalamus between 18 and 29 weeks of gestation, which corresponds to the start of production of growth hormone and other somatotropes in fetuses.
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