George Beadle

George Beadle

ForMemRS
George Beadle; ForMemRS
Born	George Wells Beadle; October 22, 1903; Wahoo, Nebraska, U.S.
Died	June 9, 1989 (aged 85); Pomona, California, U.S.
Alma mater	University of Nebraska (BS) ; Cornell University (MS, PhD)
Known for	One gene-one enzyme hypothesis; Gene regulation of biochemical events within cells;
Awards	Member of the National Academy of Sciences (1944); Albert Lasker Award for Basic Medical Research (1950); Mendel Medal (1958); Nobel Prize in Physiology or Medicine (1958); Foreign Member of the Royal Society (1960); Thomas Hunt Morgan Medal (1984);
	Scientific career
Fields	Genetics
Institutions	California Institute of Technology; University of Chicago; Harvard University; Stanford University;
Thesis	Genetical and Cytological Studies of Mendelian Asynapsis in Zea mays (1930)
Doctoral advisor	Rollins A. Emerson; Lester W. Sharp;
Other academic advisors	Franklin D. Keim; Thomas Hunt Morgan (post-doc);
Doctoral students	Robert Metzenberg;
Other notable students	Norman Horowitz (post-doc); Herschel K. Mitchell (post-doc); William D. McElroy (post-doc); Clement Markert (post-doc);

George Wells Beadle (October 22, 1903 – June 9, 1989) was an American geneticist. In 1958 he shared one-half of the Nobel Prize in Physiology or Medicine with Edward Tatum for their discovery of the role of genes in regulating biochemical events within cells. He also served as the 7th President of the University of Chicago.

Beadle and Tatum's key experiments involved exposing the bread mold Neurospora crassa to x-rays, causing mutations. In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways. These experiments led them to propose a direct link between genes and enzymatic reactions, known as the One gene-one enzyme hypothesis.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.