Galactokinase

Galactokinase 2
Galactokinase 2
Identifiers
Symbol	GALK2
NCBI gene	2585
HGNC	4119
OMIM	137028
RefSeq	NM_002044
UniProt	Q01415
Other data
EC number	2.7.1.6
Locus	Chr. 15
Structures
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Structures	Swiss-model
Domains	InterPro

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Structures	Swiss-model
Domains	InterPro

Galactokinase 1
Galactokinase 1
	Cartoon structure of a human galactokinase 1 monomer in complex with galactose (red) and an ATP analogue (orange). A magnesium ion is visible as a green sphere. (From PDB: 1WUU)
Identifiers
Symbol	GALK1
Alt. symbols	GALK
NCBI gene	2584
HGNC	4118
OMIM	604313
RefSeq	NM_000154
UniProt	P51570
Other data
EC number	2.7.1.6
Locus	Chr. 17 q23-q25
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule of ATP. Galactokinase catalyzes the second step of the Leloir pathway, a metabolic pathway found in most organisms for the catabolism of α-D-galactose to glucose 1-phosphate. First isolated from mammalian liver, galactokinase has been studied extensively in yeast, archaea, plants, and humans.

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