GNB1

GNB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4KFM, 4PNK, 3KRX, 3KRW, 1GG2, 1OMW, 1GP2, 3AH8, 1XHM, 1TBG, 3PSC, 3PVU, 3UZS, 3CIK, 3PVW, 3V5W, 5HE2, 5HE0, 5HE3, 5HE1
Identifiers
Aliases	GNB1, G protein subunit beta 1, MRD42, MDS, HG2A
External IDs	OMIM: 139380 MGI: 95781 HomoloGene: 55532 GeneCards: GNB1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	1,891,117 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	155,643,726 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; secondary oocyte; ; prefrontal cortex; ; Region I of hippocampus proper; ; orbitofrontal cortex; ; superior vestibular nucleus; ; stromal cell of endometrium; ; Brodmann area 10; ; parietal lobe; ; caput epididymis;
	Top expressed in
	retinal pigment epithelium; ; visual cortex; ; entorhinal cortex; ; superior frontal gyrus; ; aortic valve; ; cingulate gyrus; ; cumulus cell; ; ascending aorta; ; supraoptic nucleus; ; corneal stroma;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	spectrin binding; type 1 angiotensin receptor binding; protein-containing complex binding; signal transducer activity; protein binding; GTPase activity; GTPase binding; G protein-coupled receptor binding; alkylglycerophosphoethanolamine phosphodiesterase activity;
Cellular component	extracellular vesicle; cell body; membrane; photoreceptor inner segment; myelin sheath; plasma membrane; photoreceptor outer segment; intracellular anatomical structure; lysosomal membrane; dendrite; photoreceptor disc membrane; heterotrimeric G-protein complex; photoreceptor outer segment membrane; extracellular exosome; cytosol;
Biological process	cellular response to catecholamine stimulus; G protein-coupled acetylcholine receptor signaling pathway; adenylate cyclase-activating dopamine receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; cellular response to glucagon stimulus; cellular response to prostaglandin E stimulus; platelet activation; cardiac muscle cell apoptotic process; phospholipase C-activating G protein-coupled receptor signaling pathway; retina development in camera-type eye; Ras protein signal transduction; cell population proliferation; cellular response to hypoxia; sensory perception of taste; signal transduction; rhodopsin mediated signaling pathway; protein heterotrimerization; Wnt signaling pathway, calcium modulating pathway; protein folding; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2782
	14688
	ENSG00000078369
	ENSMUSG00000029064
	P62873
	P62874
	NM_002074; NM_001282538; NM_001282539
	NM_001160016; NM_001160017; NM_008142
	NP_001269467; NP_001269468; NP_002065
	NP_001153488; NP_001153489; NP_032168
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene.

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