GABRR1

GABRR1
Identifiers
Aliases	GABRR1, gamma-aminobutyric acid type A receptor rho1 subunit, gamma-aminobutyric acid type A receptor subunit rho1
External IDs	OMIM: 137161 MGI: 95625 HomoloGene: 20470 GeneCards: GABRR1
Gene location (Human)
Chr.	Chromosome 6 (human)
End	89,231,278 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	33,163,588 bp
RNA expression pattern
	Top expressed in
	ascending aorta; ; pancreatic ductal cell; ; tibialis anterior muscle; ; deltoid muscle; ; left coronary artery; ; testicle; ; right coronary artery; ; placenta; ; gastrocnemius muscle; ; lower lobe of lung;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	chloride channel activity; extracellular ligand-gated ion channel activity; GABA-A receptor activity; ion channel activity; transmembrane signaling receptor activity; ligand-gated ion channel activity involved in regulation of presynaptic membrane potential; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; GABA-A receptor complex; postsynaptic membrane; membrane; plasma membrane; synapse; integral component of plasma membrane; chloride channel complex; cell junction; neuron projection; glutamatergic synapse; GABA-ergic synapse;
Biological process	gamma-aminobutyric acid signaling pathway; chloride transmembrane transport; ion transport; chloride transport; chemical synaptic transmission; ion transmembrane transport; signal transduction; regulation of membrane potential; nervous system process; regulation of postsynaptic membrane potential; regulation of presynaptic membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	2569
	14408
	ENSG00000146276
	ENSMUSG00000028280
	P24046
	P56475
	NM_001256703; NM_001256704; NM_001267582; NM_002042
	NM_008075
	NP_001243632; NP_001243633; NP_001254511; NP_002033
	NP_032101
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid receptor subunit rho-1 is a protein that in humans is encoded by the GABRR1 gene.

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family.

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