Feline infectious peritonitis

Feline infectious peritonitis (FIP) is a common and aberrant immune response in cats to infection with feline coronavirus (FCoV).

Feline infectious peritonitis
FIP-infected kidney showing inflammatory response
SpecialtyInfectious diseases 
SymptomsInitial phase: common cold-like symptoms.

Later on: ataxia, muscle weakness, dysphagia.

End phase: shortness of breath, urinary incontinence, paralysis.
Usual onsetCan take up to a year for symptoms to appear after exposure to virus
Duration1-month or less average life expectancy after diagnosis, especially in kittens
CausesMutation of feline coronavirus
PreventionKeeping cats indoor to prevent the spread of feline coronavirus
TreatmentUK, Australia, Netherlands: GS-441524 (given orally as tablets) and its parent drug remdesivir (given by intravenous or subcutaneous injection)
PrognosisUsually fatal without treatment, but with GS-441524 treatment over 80% of treated cats make a full recovery.
FrequencyCommon
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