Etanidazole

Etanidazole is a nitroimidazole drug that was investigated in clinical trials for its radiosensitizing properties in cancer treatment. Administration of etanidazole results in a decrease of glutathione concentration and inhibits glutathione S-transferase. The result is that tissues become more sensitive to the ionizing radiation.

Etanidazole
Names
Preferred IUPAC name
N-(2-Hydroxyethyl)-2-(2-nitro-1H-imidazol-1-yl)acetamide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.164.363
PubChem CID
UNII
  • InChI=1S/C7H10N4O4/c12-4-2-8-6(13)5-10-3-1-9-7(10)11(14)15/h1,3,12H,2,4-5H2,(H,8,13) Y
    Key: WCDWBPCFGJXFJZ-UHFFFAOYSA-N Y
SMILES
  • O=[N+]([O-])c1nccn1CC(=O)NCCO
Properties
C7H10N4O4
Molar mass 214.181 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.