Estradiol dibutyrate

Estradiol dibutyrate (EDBu), or estradiol dibutanoate, is an estrogen medication and an estrogen ester – specifically, a diester of estradiol – which is no longer used. It was a component of Triormon Depositum, a combination formulation of estradiol dibutyrate, testosterone caproate, and hydroxyprogesterone heptanoate which was developed in the 1950s.

Estradiol dibutyrate
Clinical data
Other namesEDBu; Estradiol dibutanoate; Estradiol 3,17β-dibutanoate
Routes of
administration
Intramuscular injection
Drug classEstrogen; Estrogen ester
Identifiers
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.057.990
Chemical and physical data
FormulaC26H36O4
Molar mass412.570 g·mol−1
3D model (JSmol)
SMILES
  • O(C(CCC)=O)[C@]1CC[C@]([H])2[C@@]([H])3CCC4C=C(C=CC=4[C@@]3([H])CC[C@@]21C)OC(=O)CCC
  • InChI=1S/C26H35O4/c1-4-6-24(27)29-18-9-11-19-17(16-18)8-10-21-20(19)14-15-26(3)22(21)12-13-23(26)30-25(28)7-5-2/h9,11,16,20-22H,4-8,10,12-15H2,1-3H3/t20-,21-,22+,26+/m1/s1
  • Key:YQLMZRSLVHCBEL-CQAGSAPUSA-N
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