Esther Lederberg
Esther Miriam Zimmer Lederberg (December 18, 1922 – November 11, 2006) was an American microbiologist and a pioneer of bacterial genetics. She discovered the bacterial virus lambda phage and the bacterial fertility factor F, devised the first implementation of replica plating, and furthered the understanding of the transfer of genes between bacteria by specialized transduction.
Esther Lederberg | |
|---|---|
Stanford University laboratory | |
| Born | Esther Miriam Zimmer December 18, 1922 Bronx, New York, U.S. |
| Died | November 11, 2006 (aged 83) Stanford, California, U.S. |
| Alma mater | Hunter College, Stanford University, University of Wisconsin |
| Known for | Lambda phage, specialized transduction, replica plating, fertility factor F, Plasmid Reference Center |
| Spouses |
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| Awards | Pasteur Award, Dernham Postdoctoral Fellowship in Oncology, President of the Stanford Chapter of Sigma Xi |
| Scientific career | |
| Fields | Microbiology Microbial Genetics |
| Institutions | Stanford University University of Wisconsin |
| Doctoral advisor | R. A. Brink |
Lederberg also founded and directed the now-defunct Plasmid Reference Center at Stanford University, where she maintained, named, and distributed plasmids of many types, including those coding for antibiotic resistance, heavy metal resistance, virulence, conjugation, colicins, transposons, and other unknown factors.
As a woman in a male-dominated field and the wife of Nobel laureate Joshua Lederberg, Esther Lederberg struggled for professional recognition. Despite her foundational discoveries in the field of microbiology, she was never offered a tenured position at a university. Textbooks often ignore her work and attribute her accomplishments to her husband.