Eschenmoser's salt
In organic chemistry, Eschenmoser's salt (named for Albert Eschenmoser) is the ionic, organic compound [(CH3)2NCH2]I. It is the iodide salt of the dimethylaminomethylene cation [(CH3)2NCH2]+.
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Preferred IUPAC name
N,N-Dimethylmethaniminium iodide | |
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3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.046.968 |
PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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SMILES
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Properties | |
C3H8NI | |
Molar mass | 185.01 g/mol |
Appearance | colorless hygroscopic crystals |
Melting point | 116 °C (241 °F; 389 K) |
decomposes | |
Hazards | |
GHS labelling: | |
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H315, H319, H335 | |
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |
The dimethylaminomethylene cation is a strong dimethylaminomethylating agent, used to prepare derivatives of the type RCH2N(CH3)2. Enolates, silyl enol ethers, and even more acidic ketones undergo efficient dimethylaminomethylation. Once prepared, such tertiary amines can be further methylated and then subjected to base-induced elimination to afford methylidenated ketones. The salt was first prepared by the group of Albert Eschenmoser after whom the reagent is named.
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