Ephrin B1

EFNB1
Identifiers
Aliases	EFNB1, CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2, ephrin B1
External IDs	OMIM: 300035 MGI: 102708 HomoloGene: 3263 GeneCards: EFNB1
Gene location (Human)
Chr.	X chromosome (human)
End	68,842,160 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	98,192,597 bp
RNA expression pattern
	Top expressed in
	right lung; ; ganglionic eminence; ; skin of abdomen; ; upper lobe of left lung; ; tibial nerve; ; sural nerve; ; canal of the cervix; ; subcutaneous adipose tissue; ; left ventricle; ; gallbladder;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; renal corpuscle; ; lip; ; yolk sac; ; hair follicle; ; ganglionic eminence; ; left lung; ; molar; ; left colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; ephrin receptor binding; protein tyrosine kinase activity;
Cellular component	integral component of membrane; nucleus; extracellular exosome; membrane; membrane raft; integral component of plasma membrane; synapse; cytoplasm; plasma membrane;
Biological process	positive regulation of T cell proliferation; nervous system development; cell-cell signaling; T cell costimulation; multicellular organism development; neural crest cell migration; cell differentiation; cell adhesion; embryonic pattern specification; axon guidance; ephrin receptor signaling pathway; peptidyl-tyrosine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	1947
	13641
	ENSG00000090776
	ENSMUSG00000031217
	P98172
	P52795
	NM_004429
	NM_010110
	NP_004420
	NP_034240
	Wikidata
View/Edit Human	View/Edit Mouse

Ephrin B1 is a protein that in humans is encoded by the EFNB1 gene. It is a member of the ephrin family. The encoded protein is a type I membrane protein and a ligand of Eph-related receptor tyrosine kinases. It may play a role in cell adhesion and function in the development or maintenance of the nervous system.

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