Endothelin receptor

endothelin receptor type B
endothelin receptor type B
Identifiers
Symbol	EDNRB
Alt. symbols	HSCR2, HSCR
NCBI gene	1910
HGNC	3180
OMIM	131244
RefSeq	NM_000115
UniProt	P24530
Other data
Locus	Chr. 13 q22
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Search for
Structures	Swiss-model
Domains	InterPro

endothelin receptor type A
endothelin receptor type A
Identifiers
Symbol	EDNRA
NCBI gene	1909
HGNC	3179
OMIM	131243
RefSeq	NM_001957
UniProt	P25101
Other data
Locus	Chr. 4 q31.2
Structures
Search for
Structures	Swiss-model
Domains	InterPro

There are at least four known endothelin receptors, ET_A, ET_B1, ET_B2 and ET_C, all of which are G protein-coupled receptors whose activation result in elevation of intracellular-free calcium, which constricts the smooth muscles of the blood vessels, raising blood pressure, or relaxes the smooth muscles of the blood vessels, lowering blood pressure, among other functions.

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