Endosulfan
Endosulfan is an off-patent organochlorine insecticide and acaricide that is being phased out globally. It became a highly controversial agrichemical due to its acute toxicity, potential for bioaccumulation, and role as an endocrine disruptor. Because of its threats to human health and the environment, a global ban on the manufacture and use of endosulfan was negotiated under the Stockholm Convention in April 2011. The ban took effect in mid-2012, with certain uses exempted for five additional years. More than 80 countries, including the European Union, Australia, New Zealand, several West African nations, the United States, Brazil, and Canada had already banned it or announced phase-outs by the time the Stockholm Convention ban was agreed upon. It is still used extensively in India and China despite laws against its use. It is also used in a few other countries. It is produced by the Israeli firm Makhteshim Agan and several manufacturers in India and China. On May 13, 2011, the India Supreme Court ordered a ban on the production and sale of endosulfan in India, pending further notice.
Names | |
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IUPAC name
6,7,8,9,10,10-Hexachloro-1,5,5a,6,9,9a-hexahydro- 6,9-methano-2,4,3-benzodioxathiepine-3-oxide | |
Other names
Benzoepin, Endocel, Parrysulfan, Phaser, Thiodan, Thionex | |
Identifiers | |
3D model (JSmol) |
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1262315 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.003.709 |
EC Number |
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KEGG | |
PubChem CID |
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RTECS number |
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UNII | |
UN number | 2761 |
CompTox Dashboard (EPA) |
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SMILES
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Properties | |
C9H6Cl6O3S | |
Molar mass | 406.90 g·mol−1 |
Appearance | Brown crystals |
Odor | slight sulfur dioxide odor |
Density | 1.745 g/cm3 |
Melting point | 70 to 100 °C (158 to 212 °F; 343 to 373 K) |
Boiling point | decomposes |
0.33 mg/L | |
Vapor pressure | 0.00001 mmHg (25 °C) |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
T, Xi, N |
GHS labelling: | |
Danger | |
H301, H302, H410 | |
P264, P270, P273, P301+P310, P301+P312, P321, P330, P391, P405, P501 | |
NFPA 704 (fire diamond) |
2
1
0 |
Flash point | noncombustible |
NIOSH (US health exposure limits): | |
PEL (Permissible) |
none |
REL (Recommended) |
TWA 0.1 mg/m3 [skin] |
IDLH (Immediate danger) |
N.D. |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references |