Elastin

ELN
Identifiers
Aliases	ELN, SVAS, WBS, WS, elastin, ADCL1
External IDs	OMIM: 130160 GeneCards: ELN
Gene location (Human)
Chr.	Chromosome 7 (human)
End	74,069,907 bp
RNA expression pattern
	Top expressed in
	ascending aorta; ; right coronary artery; ; right lung; ; popliteal artery; ; gastric mucosa; ; left coronary artery; ; upper lobe of left lung; ; gallbladder; ; canal of the cervix; ; left uterine tube;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	extracellular matrix structural constituent; protein binding; extracellular matrix constituent conferring elasticity; extracellular matrix binding;
Cellular component	extracellular region; elastic fiber; extracellular matrix; collagen-containing extracellular matrix;
Biological process	animal organ morphogenesis; cell population proliferation; extracellular matrix disassembly; extracellular matrix organization; blood circulation; respiratory gaseous exchange by respiratory system; outflow tract morphogenesis; aortic valve morphogenesis; skeletal muscle tissue development; regulation of actin filament polymerization; stress fiber assembly; regulation of smooth muscle cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	2006
	n/a
	ENSG00000049540
	n/a
	P15502
	n/a
NM_000501; NM_001081752; NM_001081753; NM_001081754; NM_001081755;
	NM_001278912; NM_001278913; NM_001278914; NM_001278915; NM_001278916; NM_001278917; NM_001278918; NM_001278939
	n/a
NP_000492; NP_001075221; NP_001075222; NP_001075223; NP_001075224;
	NP_001265841; NP_001265842; NP_001265843; NP_001265844; NP_001265845; NP_001265846; NP_001265847; NP_001265868
	n/a
	Wikidata
View/Edit Human

Elastin is a protein that in humans is encoded by the ELN gene. Elastin is a key component of the extracellular matrix in gnathostomes (jawed vertebrates). It is highly elastic and present in connective tissue allowing many tissues in the body to resume their shape after stretching or contracting. Elastin helps skin to return to its original position when it is poked or pinched. Elastin is also an important load-bearing tissue in the bodies of vertebrates and used in places where mechanical energy is required to be stored.

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