ETS transcription factor family

In the field of molecular biology, the ETS (E26 transformation-specific or E-twenty-six. (Erythroblast Transformation Specific)) family is one of the largest families of transcription factors and is unique to animals. There are 29 genes in humans, 28 in the mouse, 10 in Caenorhabditis elegans and 9 in Drosophila. The founding member of this family was identified as a gene transduced by the leukemia virus, E26. The members of the family have been implicated in the development of different tissues as well as cancer progression.

Ets-domain
Structure of Ets-1 DNA binding autoinhibition.
Identifiers
SymbolEts
PfamPF00178
Pfam clanCL0123
InterProIPR000418
SMARTSM00413
PROSITEPDOC00374
SCOP21r36 / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1awc, 1bc7, 1bc8, 1dux, 1fli, 1gvj, 1hbx, 1k6o, 1k78, 1k79, 1k7a, 1md0, 1mdm, 1pue, 1r36, 1wwx, 1yo5, 2nny, 2stt, 2stw
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