ERG3
ERG3 or sterol C-5 desaturase is a fungal enzyme originally from Saccharomyces cerevisiae, the human ortholog of ERG3 is SC5D. ERG3 localizes to both the endoplasmic reticulum and vesicles, catalyzes the C5(6)-dehydrogenation of episterol to 5-dehydroepisterol, 5-Dehydroepisterol will be further converted into ergosterol.
| Sterol C-5 desaturase | |
|---|---|
| Identifiers | |
| Organism | |
| Symbol | ERG3 |
| Alt. symbols | SC5D, SYR1 |
| Entrez | 850745 |
| HomoloGene | 5044 |
| RefSeq (mRNA) | NM_001181943 |
| Other data | |
| EC number | 1.14.19.20 |
| Chromosome | XII: 0.25 - 0.25 Mb |
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