EIF1AX

EIF1AX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1D7Q, 3ZJY, 4KZY, 4KZZ
Identifiers
Aliases	EIF1AX, EIF1A, EIF1AP1, EIF4C, eIF-1A, eIF-4C, eukaryotic translation initiation factor 1A, X-linked, eukaryotic translation initiation factor 1A X-linked
External IDs	OMIM: 300186 MGI: 95298 HomoloGene: 20364 GeneCards: EIF1AX
Gene location (Human)
Chr.	X chromosome (human)
End	20,141,838 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	46,749,523 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; biceps brachii; ; pons; ; ganglionic eminence; ; pericardium; ; postcentral gyrus; ; Brodmann area 23; ; cerebellar vermis; ; islet of Langerhans; ; superior frontal gyrus;
	Top expressed in
	seminal vesicula; ; otic placode; ; saccule; ; pineal gland; ; corneal stroma; ; calvaria; ; primitive streak; ; Paneth cell; ; morula; ; abdominal wall;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	translation factor activity, RNA binding; protein binding; translation initiation factor activity; RNA binding;
Cellular component	cytosol;
Biological process	translational initiation; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	1964
	13664
	ENSG00000173674
	ENSMUSG00000057561
	P47813
	Q60872
	NM_001412
	NM_010120; NM_001374654
	NP_001403
	NP_034250
	Wikidata
View/Edit Human	View/Edit Mouse

Eukaryotic translation initiation factor 1A, X-chromosomal (eIF1A) is a protein that in humans is encoded by the EIF1AX gene. This gene encodes an essential eukaryotic translation initiation factor. The protein is a component of the 43S pre-initiation complex (PIC), which mediates the recruitment of the small 40S ribosomal subunit to the 5' cap of messenger RNAs.

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