EBI3

EBI3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	7U7N, 7Z0L, 7ZG0, 7ZXK, 8D85
Identifiers
Aliases	EBI3, IL-27B, IL27B, Epstein-Barr virus induced 3, IL35B
External IDs	OMIM: 605816 MGI: 1354171 HomoloGene: 4207 GeneCards: EBI3
Gene location (Human)
Chr.	Chromosome 19 (human)
End	4,237,528 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	56,264,022 bp
RNA expression pattern
	Top expressed in
	placenta; ; spleen; ; appendix; ; lymph node; ; gallbladder; ; right adrenal gland; ; right coronary artery; ; left adrenal gland; ; left uterine tube; ; ascending aorta;
	Top expressed in
	splanchnocranium; ; rib; ; hyoid bone; ; humerus; ; sphenoid bone; ; Meckel's cartilage; ; lesser wing of sphenoid bone; ; saccule; ; basisphenoid; ; blood;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine receptor activity; cytokine activity; interleukin-27 receptor binding; protein binding; ciliary neurotrophic factor receptor activity; cytokine binding;
Cellular component	extracellular region; plasma membrane; membrane; extracellular space; endoplasmic reticulum lumen; external side of plasma membrane; receptor complex; ciliary neurotrophic factor receptor complex; CNTFR-CLCF1 complex;
Biological process	T-helper 1 type immune response; T cell proliferation; humoral immune response; positive regulation of alpha-beta T cell proliferation; regulation of signaling receptor activity; interleukin-27-mediated signaling pathway; interleukin-35-mediated signaling pathway; ciliary neurotrophic factor-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10148
	50498
	ENSG00000105246
	ENSMUSG00000003206
	Q14213
	O35228
	NM_005755
	NM_015766
	NP_005746
	NP_056581
	Wikidata
View/Edit Human	View/Edit Mouse

Epstein-Barr virus induced gene 3, also known as interleukin-27 subunit beta or IL-27B, is a protein which in humans is encoded by the EBI3 gene.

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